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Quick answers
Did Orion Buske co-found PhenoTips?
Yes. PhenoTips' own team page, checked September 22, 2026, lists him as "Co-Founder and Chief Executive Officer". University of Toronto Entrepreneurship, on April 7, 2026, described him as "CEO and Co-Founder of PhenoTips" and said the company was "Founded in 2014 out of research at SickKids and the University of Toronto".
Who are his co-founders?
PhenoTips' team page, checked September 22, 2026, lists two other co-founders: Pawel Buczkowicz, Co-Founder and Chief Operating Officer, and Michael Brudno, Co-Founder and Chairman of the Board.
Is he still running PhenoTips?
Yes, as far as can be verified today. The company's team page, checked September 22, 2026, still lists him as Co-Founder and Chief Executive Officer, and University of Toronto Entrepreneurship quoted him in that role on April 7, 2026, on the launch of a national AI initiative in genomic medicine. A PhenoTips webinar page dated May 22, 2024 called him "the Chief Technology Officer of PhenoTips", so the move to chief executive appears to have come after that.
What is his background?
His personal site, checked September 22, 2026, says "I received a PhD in Computer Science from the University of Toronto, with a fellowship at SickKids Hospital", with doctoral work on "software and algorithms to help specialists solve rare genetic diseases"; the thesis linked there is dated 2016. On the DNA Today podcast, published March 26, 2021, he was described as having led the technical development of PhenomeCentral, the Matchmaker Exchange, PatientKind and RareConnect.