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Cyclica

Cyclica was a Toronto AI drug-discovery company. Founded in 2013 by Jason Mitakidis and Naheed Kurji, it screened molecules against the whole proteome instead of one target at a time, raised a $23M Series B in 2020, and was acquired by Recursion Pharmaceuticals for US$40M in May 2023. It no longer operates independently.

Acquired — Acquired by Recursion Pharmaceuticals for US$40M in May 2023; no longer operates independently.

AI drug discoveryTorontoFounded 2013recursion.com
US$40Mall-stock price Recursion paid, announced 8 May 2023Recursion press release 2023-05-08
$23MSeries B led by Drive Capital, closed 24 June 2020BetaKit 2020-06-24
~60staff at the time of the Recursion acquisitionBetaKit 2023-05-08
~40employees in July 2020, up from 15-16 in May 2017 — Kurji's own figures on stageTechTO stage 2020-09-01
~$38Mtotal raised over seven years as of July 2020 — Kurji's own figure on stageTechTO stage 2020-09-01

The people

What they build

MatchMakerDeep-learning engine that predicted how a small molecule interacts across the proteome — the polypharmacology screen Cyclica was known for. Folded into Recursion's platform after the 2023 acquisition.Product page ↗
POEMPareto Optimal Embedding Model, for predicting molecular properties. Also absorbed into Recursion's platform.Product page ↗

Open roles via the TechTO Job Board

Working at Cyclica

Browse open roles across the community on the TechTO Job Board — Canada’s most connected tech network. Cyclica’s roles show up here whenever they post.

Open roles on the TechTO Job Board ↗Or their own careers page: recursion.com/careers ↗

Jobs live on jobs.techto.org — the only structured source. We link to it rather than scraping career sites, so the board is always the source of truth.

On the TechTO stage

Every talk is searchable — ask the archive about Cyclica

About

Cyclica inverted the usual drug-discovery question. Rather than designing one key for one lock, it predicted every protein a small molecule would touch — polypharmacology — to catch side effects and find new uses earlier. Kurji laid the analogy out on the TechTO stage in July 2020, days after closing a $23M Series B led by Drive Capital. The company also moved from selling software to the top 50 pharma companies toward co-founding biotechs and taking ownership in their programs. Recursion announced the acquisition on 8 May 2023 and closed it on 25 May 2023; the team was fully integrated and Toronto became Recursion's largest office outside its Salt Lake City headquarters. The brand is gone — cyclica.com is now an unrelated used-construction-equipment marketplace.

Backers

Drive Capital (Series B lead, board seat), Chiesi Farmaceutici and GreenSky Capital — confirmed by BetaKit's 2020-06-24 Series B coverage. Kurji said on stage that earlier capital came from friends and family, angel networks and early-stage VCs, and that about $14.5M of it was supported by government grants and non-dilutive financing.

Quick answers

What did Cyclica do?

It used AI and computational biophysics to predict how a drug interacts with every protein in the body rather than a single target, so scientists could spot side effects and new uses earlier. Its main engines were MatchMaker and POEM.

Who founded Cyclica?

Jason Mitakidis and Naheed Kurji, in Toronto in 2013. Mitakidis had pitched the proteome-wide screening idea at a University of Toronto competition; Kurji joined as CFO and became President and CEO in 2016.

What happened to Cyclica?

Recursion Pharmaceuticals acquired it for US$40M in stock — announced 8 May 2023, closed 25 May 2023. The team was fully integrated into Recursion and Toronto became Recursion's largest office outside its headquarters. Cyclica no longer operates as its own company.

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Maintained by TechTO · facts sourced and dated · last reviewed Jul 15, 2026