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Pentavere

Pentavere is a Toronto health-AI company whose DARWEN engine extracts evidence from unstructured clinical notes — progress notes, dictation, scanned forms — and turns it into coded, structured data used to find patients who are eligible for a treatment but not receiving it. Founded 2016; now owned by HEALWELL AI.

Health AITorontoFounded 2016pentavere.ai
85,000patient records processed in the St. Michael's Hospital opioid-disorder validation study, with 76 unique clinical features extractedTechTO stage 2018-06-20
Under 2%of physicians actually entered a daily morphine equivalent score into the EMR, even with a workflow built for it — the gap Leibtag used to argue for extracting from notes insteadTechTO stage 2018-06-20
~$14Mpaid by HEALWELL AI in July 2025 for the remaining 49% of Pentavere, taking full ownershipNewsweek, July 2025

The people

Aaron LeibtagCo-founder & CEO · 1 TechTO talk
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Steven AvivCo-founder & CTOprofile coming

What they build

DARWEN AIThe company's AI engine. It reads unstructured clinical documentation and outputs structured, coded data — clinical features linked to SNOMED, ICD and MeSH, with drug dose, route and frequency normalized. Used to identify patients eligible for approved medications or interventions they aren't receiving.Product page ↗

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On the TechTO stage

Every talk is searchable — ask the archive about Pentavere

About

Aaron Leibtag and Steven Aviv started Pentavere in Toronto in 2016. The premise, as Leibtag put it on the TechTO stage in June 2018: about 80% of the health information the system creates is never used, because it sits buried in unstructured text — the progress notes physicians write for themselves, dictated transcriptions, and digitized forms. DARWEN reads that text and outputs row-and-column data, with every clinical feature linked back to international ontologies (SNOMED, ICD, MeSH) and drug dose, route and frequency normalized. Rather than sell a product first, the company embedded itself in a hospital and validated the technology through clinical studies at St. Michael's Hospital in partnership with the Biomedical Zone, with pharmaceutical sponsors funding development through research studies — which is how it grew without venture capital. In the 2018 demo Leibtag described an opioid-disorder study across 85,000 records, extracting 76 unique clinical features including socio-economic factors and notations of double-doctoring that never appear in structured EMR fields. Pentavere later won a Prix Galien award and was a finalist in Newsweek's 2025 AI Impact Awards. HEALWELL AI took a majority position in December 2023 and bought the remaining 49% in July 2025 for roughly $14 million. Leibtag remains co-founder and CEO.

Backers

No venture capital. Leibtag funded development through pharmaceutical-sponsored research studies rather than a VC round (Newsweek, July 2025). HEALWELL AI acquired a majority position, completed December 2023, and exercised its call option on the remaining 49% in July 2025, taking full ownership.

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Quick answers

What is DARWEN AI?

Pentavere's engine for reading unstructured health data. It takes clinical text — progress notes, dictation, scanned forms — and produces structured row-and-column data, coding each clinical feature to SNOMED, ICD or MeSH and normalizing drug dose, route and frequency. The point is to surface patients who are eligible for an approved medication or intervention but not receiving it.

Who owns Pentavere?

HEALWELL AI. It completed the acquisition of a majority position in December 2023, then exercised its call option on the remaining 49% in July 2025 for roughly $14 million. Pentavere still operates under its own name and Aaron Leibtag is still co-founder and CEO.

How was the technology validated?

Inside a hospital rather than in a lab. Pentavere ran validation work at St. Michael's Hospital in partnership with the Biomedical Zone, including an opioid-disorder study across 85,000 records that extracted 76 clinical features. The company has since published peer-reviewed results.

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Maintained by TechTO · facts sourced and dated · last reviewed Jul 14, 2026